“Our studies of several classical acupoints indicate that acupuncture modulates the limbic network, an important intrinsic regulatory system of the human brain. The network shows significant overlap with the default mode of the resting brain. These associated autonomic nervous function changes can be demonstrated by physiological monitoring.”
The participants in the EA group received EA treatment with a mixed current of 2 Hz/120 Hz at 12 acupuncture points (bilateral Zusanli [ST36], Xuanzhong [GB39], Yinlingquan [SP9], Sanyinjiao [SP6], Taichong [LR3], and Zulinqi [GB41]) twice per week for 8 weeks. Depending on the sites of pain, the additional acupuncture point Bafeng (EX-LE10) was available.
“To our knowledge, this is the first multicenter randomized controlled trial to evaluate the effectiveness and safety of EA treatment for the management in PDN. One limitation is that neither a placebo nor sham EA was used as an active control; therefore, the possibility of a placebo effect was not excluded. In conclusion, the results of this study
demonstrate that EA treatment is effective for reducing pain and improving sleep disturbance and quality of life in PDN. In addition, EA treatment was well tolerated and safe during this study. These findings suggest that EA treatment may be recommended as a nonpharmacological treatment for pain reduction in PDN.”
our findings support acupuncture as an effective treatment in alleviating pain among cancer patients and survivors, particularly malignancy-related and surgery-induced pain. To expand the application of acupuncture on cancer-related pain, investigators should clearly define the types of cancer pain (e.g. malignancy related pain) as inclusion criteria in the future studies.
We found that each acupoint had a distinct spatial pattern of indications, and that the patterns were strongly associated with routes of the meridian.
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