Herbal Medicines, Integrative Cancer Care

Survival Benefits of Western and Traditional Chinese Medicine Treatment for Patients With Pancreatic Cancer

Survival Benefits of Western and Traditional Chinese Medicine Treatment for Patients With Pancreatic Cancer

We conclude, from this small retrospective study, that TCM treatment was associated with a survival benefit in patients with pancreatic cancer. In addition, TCM in combination with WM would be a better optimal treatment for patients with pancreatic cancer to improve survival time. More importantly, we provide TCM practitioners with a proposal that heat-clearing, diuresis-promoting and detoxification TCM treatment may improve the efficacy of TCM in patients with pancreatic cancer.

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Three Kinds of Supporting TCM Treatment Methods on Pancreatic Cancer and Most Commonly Used Herbs of Each Method
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Herbal Medicines, Integrative Cancer Care

Characteristics of Chinese herbal medicine usage and its effect on survival of lung cancer patients in Taiwan

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Characteristics of Chinese herbal medicine usage and its effect on survival of lung cancer patients in Taiwan

Results

The CHM group was characterized by a longer follow up time and more cases of hyperlipidemia and liver cirrhosis. This group exhibited a lower mortality hazard ratio (0.48, 95% confidence interval [0.39–0.61], p < 0.001), after adjusting for comorbidities. The trend was also observed that the cumulative survival probability was higher in CHM than in non-CHM users (p < 0.0001, log rank test). Analysis of their CHM prescription pattern revealed that Bu-Zhong-Yi-Qi-Tang (BZYQT), Xiang-Sha-Liu-Jun-Zi-Tang (XSLJZT), and Bai-He-Gu-Jin-Tang (BHGJT); and Bei-Mu (BM), Xing-Ren (XR) and Ge-Gen (GG) were found to be the top three formulas and herbs, respectively. Among them, BM was the core CHM of the major cluster, and Jie-Geng (JG) and Mai-Men-Dong-Tang (MMDT) were important CHMs by CHM network analysis.

Conclusion

The use of CHM as an adjunctive therapy may reduce the mortality hazard ratio of lung cancer patients.

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Herbal Medicines, Integrative Cancer Care

Prescription of Chinese herbal products is associated with a decreased risk of invasive breast cancer

Prescription of Chinese herbal products is associated with a decreased risk of invasive breast cancer

“Consumption of CHPs reduces the incidence of invasive breast cancer. Although the mechanism of action of these products is unclear, their use as a preventive agent for breast cancer is appropriate for many women at an increased risk of breast cancer.”

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  • The best result is with SWT (Siwutang in Chinese, Samultang in Korean).사물탕에 대한 이미지 검색결과

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Integrative Cancer Care

Acupuncture for Chemoradiation Therapy-Related Dysphagia in Head and Neck Cancer.

Acupuncture for Chemoradiation Therapy-Related Dysphagia in Head and Neck Cancer: A Pilot Randomized Sham-Controlled Trial

“A blinded, sham-controlled, randomized clinical trial to evaluate the effectiveness of verum acupuncture in treating dysphagia-related QOL in patients with advanced stage of HNC undergoing intense CRT found the procedure to be feasible, safe, and well tolerated. Dysphagia-related QOL improved with both active acupuncture and sham acupuncture.”

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Figure 1.

Acupuncture points used for chemoradiation-related dysphagia in head and neck cancer. To avoid the radiation field, acupuncture points needled before week 4 after CRT (phase 1, solid round circles) were selected to avoid the chin and neck area. Additional points were added at week 4 after CRT visit (phase 2, solid diamonds) and at the week 12 after CRT (phase 3, solid triangles). Electrostimulation was added starting with the third visit.

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Integrative Cancer Care

Do not get so fat. Excessive adipose tissue can induce cancer.

Fibroblast growth factor receptor is a mechanistic link between visceral adiposity and cancer

Oncogene advance online publication 7 August 2017

Abstract

Epidemiological evidence implicates excess adipose tissue in increasing cancer risk. Despite a steeply rising global prevalence of obesity, how adiposity contributes to transformation (stage a non-tumorigenic cell undergoes to become malignant) is unknown. To determine the factors in adipose tissue that stimulate transformation, we used a novel ex vivosystem of visceral adipose tissue (VAT)-condition medium-stimulated epithelial cell growth in soft agar. To extend this system in vivo, we used a murine lipectomy model of ultraviolet light B-induced, VAT-promoted skin tumor formation. We found that VAT from mice and obese human donors stimulated growth in soft agar of non-tumorigenic epithelial cells. The difference in VAT activity was associated with fibroblast growth factor-2 (FGF2) levels. Moreover, human and mouse VAT failed to stimulate growth in soft of agar in cells deficient in FGFR-1 (FGF2 receptor). We also demonstrated that circulating levels of FGF2 were associated with non-melanoma tumor formation in vivo. These data implicate FGF2 as a major factor VAT releases to transform epithelial cells—a novel, potential pathway of VAT-enhanced tumorigenesis. Strategies designed to deplete VAT stores of FGF2 or inhibit FGFR-1 in abdominally obese individuals may be important cancer prevention strategies as well as adjuvant therapies for improving outcomes.

Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

 

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Integrative Cancer Care

You are quite “Lucky”, if you are not a cancer patient.

Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention

Science  24 Mar 2017:
Vol. 355, Issue 6331, pp. 1330-1334

Fig 3. 유전적 요인(Hereditary), 환경적 요인(Environmental)에 비해서, DNA replication에 의한 driver mutation (Replicative)의 비율이 여러 암종을 통틀어서도 매우 높다.jpg

Cancer and the unavoidable R factor

Most textbooks attribute cancer-causing mutations to two major sources: inherited and environmental factors. A recent study highlighted the prominent role in cancer of replicative (R) mutations that arise from a third source: unavoidable errors associated with DNA replication. Tomasetti et al. developed a method for determining the proportions of cancer-causing mutations that result from inherited, environmental, and replicative factors (see the Perspective by Nowak and Waclaw). They found that a substantial fraction of cancer driver gene mutations are indeed due to replicative factors. The results are consistent with epidemiological estimates of the fraction of preventable cancers.

Science, this issue p. 1330; see also p. 1266

Abstract

Cancers are caused by mutations that may be inherited, induced by environmental factors, or result from DNA replication errors (R). We studied the relationship between the number of normal stem cell divisions and the risk of 17 cancer types in 69 countries throughout the world. The data revealed a strong correlation (median = 0.80) between cancer incidence and normal stem cell divisions in all countries, regardless of their environment. The major role of R mutations in cancer etiology was supported by an independent approach, based solely on cancer genome sequencing and epidemiological data, which suggested that R mutations are responsible for two-thirds of the mutations in human cancers. All of these results are consistent with epidemiological estimates of the fraction of cancers that can be prevented by changes in the environment. Moreover, they accentuate the importance of early detection and intervention to reduce deaths from the many cancers arising from unavoidable R mutations.

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Integrative Cancer Care, Medical Acupuncture

Acupuncture May Stimulate Anticancer Immunity via Activation of Natural Killer Cells

Acupuncture stimulation increases the cytotoxicity of NK cells by promoting cross talk between the neurotransmitter network and immune system.

https://www.hindawi.com/journals/ecam/2011/481625/

Evidence-Based Complementary and Alternative Medicine, Volume 2011 (2011)

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