Herbal Medicines, Integrative Cancer Care

Efficacy and Safety of the Traditional Herbal Medicine, Gamiguibi-tang, in Patients With Cancer-Related Sleep Disturbance

Efficacy and Safety of the Traditional Herbal Medicine, Gamiguibi-tang, in Patients With Cancer-Related Sleep Disturbance: A Prospective, Randomized, Wait-List-Controlled, Pilot Study

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Figure

Figure 2. Changes in the ISI (A) and BFI (B) scores in the GGBT and wait-list groups. The ends of whiskers represent the upper and lower limit of the values and columns represent 25th and 75th percentile with the median value. The connecting lines represent changes of mean values. *Represents change that was statistically significant (P < .05). White columns represent GGBT group, whereas gray columns represent wait-list group. ISI, Insomnia Severity Index; BFI, Brief Fatigue Inventory; GGBT, Gamiguibi-tang.

 

This study showed that GGBT significantly improved sleep quality and fatigue level but not depression and cognitive impairment in patients with cancer after 2 weeks of intervention without serious adverse events.

Patients with cancer have difficulty maintaining good sleep quality because of their psychosocial and physical stresses. However, standard nonpharmacological and pharmacological approaches to alleviate sleep disturbance in patients with cancer are still lacking. The duration and depth of sleep in these patients is affected by physical problems such as respiratory failure or pain, stressful decisions about cancer therapies and therapy-induced adverse events, as well as circadian disturbance caused by the cancer itself.7,24 In addition, sleep insufficiency arouses immunosuppression and increases the incidence of cardiac, metabolic, and inflammatory diseases.25,26 However, cognitive behavior therapy—one of the nonpharmacological approaches and the current standard recommendation—requires sufficient amount of time and workforce to administer. The possibilities of impaired liver or renal function due to chemotherapies or cancer-related issues call for safer pharmacological approaches for patients with cancer and survivors of cancer.

 

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Herbal Medicines, Integrative Cancer Care

Kamikihito improves cancer-related fatigue by restoring balance between the sympathetic and parasympathetic nervous systems

Kamikihito improves cancer-related fatigue by restoring balance between the sympathetic and parasympathetic nervous systems

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CONCLUSIONS:

Fatigue was more serious in patients with cancer than in control patients. Kamikihito rescued this fatigue and improved anxiety and sleepiness. It restored autonomic nervous system balance and antioxidant function.

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Herbal Medicines, Integrative Cancer Care

Survival Benefits of Western and Traditional Chinese Medicine Treatment for Patients With Pancreatic Cancer

Survival Benefits of Western and Traditional Chinese Medicine Treatment for Patients With Pancreatic Cancer

We conclude, from this small retrospective study, that TCM treatment was associated with a survival benefit in patients with pancreatic cancer. In addition, TCM in combination with WM would be a better optimal treatment for patients with pancreatic cancer to improve survival time. More importantly, we provide TCM practitioners with a proposal that heat-clearing, diuresis-promoting and detoxification TCM treatment may improve the efficacy of TCM in patients with pancreatic cancer.

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Three Kinds of Supporting TCM Treatment Methods on Pancreatic Cancer and Most Commonly Used Herbs of Each Method
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Herbal Medicines, Integrative Cancer Care

Characteristics of Chinese herbal medicine usage and its effect on survival of lung cancer patients in Taiwan

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Characteristics of Chinese herbal medicine usage and its effect on survival of lung cancer patients in Taiwan

Results

The CHM group was characterized by a longer follow up time and more cases of hyperlipidemia and liver cirrhosis. This group exhibited a lower mortality hazard ratio (0.48, 95% confidence interval [0.39–0.61], p < 0.001), after adjusting for comorbidities. The trend was also observed that the cumulative survival probability was higher in CHM than in non-CHM users (p < 0.0001, log rank test). Analysis of their CHM prescription pattern revealed that Bu-Zhong-Yi-Qi-Tang (BZYQT), Xiang-Sha-Liu-Jun-Zi-Tang (XSLJZT), and Bai-He-Gu-Jin-Tang (BHGJT); and Bei-Mu (BM), Xing-Ren (XR) and Ge-Gen (GG) were found to be the top three formulas and herbs, respectively. Among them, BM was the core CHM of the major cluster, and Jie-Geng (JG) and Mai-Men-Dong-Tang (MMDT) were important CHMs by CHM network analysis.

Conclusion

The use of CHM as an adjunctive therapy may reduce the mortality hazard ratio of lung cancer patients.

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Integrative Cancer Care, News!

 SIO’s 12th International Conference Program.

I am heading to Boston!

SIO’s 12th International Conference will be held November 14-16, 2015, with a theme of “Integrative Innovation” preceded by a first-ever Joint Conference on November 14 presented by SIO, the Society for Acupuncture Research, and Fascia Research Society.
Click here for Program

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