Herbal Medicines, Integrative Cancer Care

Prescription of Chinese herbal products is associated with a decreased risk of invasive breast cancer

Prescription of Chinese herbal products is associated with a decreased risk of invasive breast cancer

“Consumption of CHPs reduces the incidence of invasive breast cancer. Although the mechanism of action of these products is unclear, their use as a preventive agent for breast cancer is appropriate for many women at an increased risk of breast cancer.”

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  • The best result is with SWT (Siwutang in Chinese, Samultang in Korean).사물탕에 대한 이미지 검색결과

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Integrative Cancer Care

You are quite “Lucky”, if you are not a cancer patient.

Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention

Science  24 Mar 2017:
Vol. 355, Issue 6331, pp. 1330-1334

Fig 3. 유전적 요인(Hereditary), 환경적 요인(Environmental)에 비해서, DNA replication에 의한 driver mutation (Replicative)의 비율이 여러 암종을 통틀어서도 매우 높다.jpg

Cancer and the unavoidable R factor

Most textbooks attribute cancer-causing mutations to two major sources: inherited and environmental factors. A recent study highlighted the prominent role in cancer of replicative (R) mutations that arise from a third source: unavoidable errors associated with DNA replication. Tomasetti et al. developed a method for determining the proportions of cancer-causing mutations that result from inherited, environmental, and replicative factors (see the Perspective by Nowak and Waclaw). They found that a substantial fraction of cancer driver gene mutations are indeed due to replicative factors. The results are consistent with epidemiological estimates of the fraction of preventable cancers.

Science, this issue p. 1330; see also p. 1266

Abstract

Cancers are caused by mutations that may be inherited, induced by environmental factors, or result from DNA replication errors (R). We studied the relationship between the number of normal stem cell divisions and the risk of 17 cancer types in 69 countries throughout the world. The data revealed a strong correlation (median = 0.80) between cancer incidence and normal stem cell divisions in all countries, regardless of their environment. The major role of R mutations in cancer etiology was supported by an independent approach, based solely on cancer genome sequencing and epidemiological data, which suggested that R mutations are responsible for two-thirds of the mutations in human cancers. All of these results are consistent with epidemiological estimates of the fraction of cancers that can be prevented by changes in the environment. Moreover, they accentuate the importance of early detection and intervention to reduce deaths from the many cancers arising from unavoidable R mutations.

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Integrative Cancer Care

Preventable Incidence and Mortality of Carcinoma Associated With Lifestyle Factors Among White Adults in the United States

A substantial cancer burden may be prevented through lifestyle modification. Primary prevention should remain a priority for cancer control.

A healthy lifestyle pattern was defined as never or past smoking (pack-years <5), no or moderate alcohol drinking (≤1 drink/d for women, ≤2 drinks/d for men), BMI of at least 18.5 but lower than 27.5, and weekly aerobic physical activity of at least 75 vigorous-intensity or 150 moderate-intensity minutes.

Preventable Incidence and Mortality of Carcinoma Associated With Lifestyle Factors Among White Adults in the United States  (JAMA Oncol. Published online May 19, 2016)

 

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