Herbal Medicines, Integrative Cancer Care

Survival Benefits of Western and Traditional Chinese Medicine Treatment for Patients With Pancreatic Cancer

Survival Benefits of Western and Traditional Chinese Medicine Treatment for Patients With Pancreatic Cancer

We conclude, from this small retrospective study, that TCM treatment was associated with a survival benefit in patients with pancreatic cancer. In addition, TCM in combination with WM would be a better optimal treatment for patients with pancreatic cancer to improve survival time. More importantly, we provide TCM practitioners with a proposal that heat-clearing, diuresis-promoting and detoxification TCM treatment may improve the efficacy of TCM in patients with pancreatic cancer.

medi-94-e1008-g001

Three Kinds of Supporting TCM Treatment Methods on Pancreatic Cancer and Most Commonly Used Herbs of Each Method
Advertisements
Standard
Herbal Medicines, Integrative Cancer Care

Characteristics of Chinese herbal medicine usage and its effect on survival of lung cancer patients in Taiwan

lung.PNG

Characteristics of Chinese herbal medicine usage and its effect on survival of lung cancer patients in Taiwan

Results

The CHM group was characterized by a longer follow up time and more cases of hyperlipidemia and liver cirrhosis. This group exhibited a lower mortality hazard ratio (0.48, 95% confidence interval [0.39–0.61], p < 0.001), after adjusting for comorbidities. The trend was also observed that the cumulative survival probability was higher in CHM than in non-CHM users (p < 0.0001, log rank test). Analysis of their CHM prescription pattern revealed that Bu-Zhong-Yi-Qi-Tang (BZYQT), Xiang-Sha-Liu-Jun-Zi-Tang (XSLJZT), and Bai-He-Gu-Jin-Tang (BHGJT); and Bei-Mu (BM), Xing-Ren (XR) and Ge-Gen (GG) were found to be the top three formulas and herbs, respectively. Among them, BM was the core CHM of the major cluster, and Jie-Geng (JG) and Mai-Men-Dong-Tang (MMDT) were important CHMs by CHM network analysis.

Conclusion

The use of CHM as an adjunctive therapy may reduce the mortality hazard ratio of lung cancer patients.

Standard
Herbal Medicines, Integrative Cancer Care

Prescription of Chinese herbal products is associated with a decreased risk of invasive breast cancer

Prescription of Chinese herbal products is associated with a decreased risk of invasive breast cancer

“Consumption of CHPs reduces the incidence of invasive breast cancer. Although the mechanism of action of these products is unclear, their use as a preventive agent for breast cancer is appropriate for many women at an increased risk of breast cancer.”

캡처

  • The best result is with SWT (Siwutang in Chinese, Samultang in Korean).사물탕에 대한 이미지 검색결과

캡처

 

Standard
Integrative Cancer Care

Acupuncture for Chemoradiation Therapy-Related Dysphagia in Head and Neck Cancer.

Acupuncture for Chemoradiation Therapy-Related Dysphagia in Head and Neck Cancer: A Pilot Randomized Sham-Controlled Trial

“A blinded, sham-controlled, randomized clinical trial to evaluate the effectiveness of verum acupuncture in treating dysphagia-related QOL in patients with advanced stage of HNC undergoing intense CRT found the procedure to be feasible, safe, and well tolerated. Dysphagia-related QOL improved with both active acupuncture and sham acupuncture.”

F1.large

Figure 1.

Acupuncture points used for chemoradiation-related dysphagia in head and neck cancer. To avoid the radiation field, acupuncture points needled before week 4 after CRT (phase 1, solid round circles) were selected to avoid the chin and neck area. Additional points were added at week 4 after CRT visit (phase 2, solid diamonds) and at the week 12 after CRT (phase 3, solid triangles). Electrostimulation was added starting with the third visit.

Standard
Herbal Medicines, Integrative Cancer Care

To improve appetite loss in patients with lung cancer undergoing chemotherapy. – Use of the herbal formula ‘YukgunjaTang’

Effect of rikkunshi-to treatment on chemotherapy-induced appetite loss in patients with lung cancer: A prospective study

Exp Ther Med. 2016 Jan; 11(1): 243–246. Published online 2015 Nov 27.
05164906view
In patients treated with CBDCA-containing chemotherapy, food intake at day 7 following the initiation of chemotherapy in the rikkunshi-to treatment group was significantly higher compared with the group not treated with rikkunshi-to (P=0.0078).
Standard
Integrative Cancer Care

Do not get so fat. Excessive adipose tissue can induce cancer.

Fibroblast growth factor receptor is a mechanistic link between visceral adiposity and cancer

Oncogene advance online publication 7 August 2017

Abstract

Epidemiological evidence implicates excess adipose tissue in increasing cancer risk. Despite a steeply rising global prevalence of obesity, how adiposity contributes to transformation (stage a non-tumorigenic cell undergoes to become malignant) is unknown. To determine the factors in adipose tissue that stimulate transformation, we used a novel ex vivosystem of visceral adipose tissue (VAT)-condition medium-stimulated epithelial cell growth in soft agar. To extend this system in vivo, we used a murine lipectomy model of ultraviolet light B-induced, VAT-promoted skin tumor formation. We found that VAT from mice and obese human donors stimulated growth in soft agar of non-tumorigenic epithelial cells. The difference in VAT activity was associated with fibroblast growth factor-2 (FGF2) levels. Moreover, human and mouse VAT failed to stimulate growth in soft of agar in cells deficient in FGFR-1 (FGF2 receptor). We also demonstrated that circulating levels of FGF2 were associated with non-melanoma tumor formation in vivo. These data implicate FGF2 as a major factor VAT releases to transform epithelial cells—a novel, potential pathway of VAT-enhanced tumorigenesis. Strategies designed to deplete VAT stores of FGF2 or inhibit FGFR-1 in abdominally obese individuals may be important cancer prevention strategies as well as adjuvant therapies for improving outcomes.

Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

 

Standard
Herbal Medicines, Integrative Cancer Care

Personalizing Chinese medicine by integrating molecular features of diseases and herb ingredient information: application to acute myeloid leukemia

16983-249012-1-PB.pdf.png

ABSTRACT

Traditional Chinese Medicine (TCM) has been widely used as a complementary medicine in Acute Myeloid Leukemia (AML) treatment. In this study, we proposed a new classification of Chinese Medicines (CMs) by integrating the latest discoveries in disease molecular mechanisms and traditional medicine theory. We screened out a set of chemical compounds on basis of AML differential expression genes and chemical-protein interactions and then mapped them to Traditional Chinese Medicine Integrated Database. 415 CMs contain those compounds and they were categorized into 8 groups according to the Traditional Chinese Pharmacology. Pathway analysis and synthetic lethality gene pairs were applied to analyze the dissimilarity, generality and intergroup relations of different groups. We defined hub CM pairs and alternative CM groups based on the analysis result and finally proposed a formula to form an effective anti-AML prescription which combined the hub CM pairs with alternative CMs according to patients’ molecular features. Our method of formulating CMs based on patients’ stratification provides novel insights into the new usage of conventional CMs and will promote TCM modernization.

Personalizing Chinese medicine by integrating molecular features of diseases and herb ingredient information: application to acute myeloid leukemia

Standard